Triamcinolone

Provider Level

RN/Paramedic

Class

Glucocorticoid / Corticosteroid

Mechanism of Action

Synthetic glucocorticoid that interacts with specific receptor proteins to regulate corticosteroid-responsive genes, producing potent anti-inflammatory and immunosuppressive effects.

Indications

Severe allergic reactions, allergic rhinitis, acute exacerbations of multiple sclerosis, acute gouty arthritis, and severe inflammatory conditions.

Contraindications

Hypersensitivity to triamcinolone, systemic fungal infections. Not for intravenous (IV) use.

Routes

IM (deep gluteal), Intra-articular, Topical. Do NOT administer IV.

Onset / Duration

Onset: Hours to days. Duration: Weeks to months (depot effect).

Adverse Effects

Upset stomach, headache, dizziness, insomnia, restlessness, anxiety, easy bruising, and immunosuppression.

Precautions & Interactions

May mask signs of infection. Can slow bone growth in children. Use caution in pregnancy and hepatic impairment.

Special Considerations

Rarely used in acute EMS/prehospital care due to delayed onset. Suspension formulations must never be given IV. Patients on chronic therapy may require stress dosing during severe illness or trauma.